Get Rid of QuickBooks Error 2147221164 Once and For All
- jamesaultman812Hy8n
- 1 day ago
- 4 min read
QuickBooks error 2147221164 is a runtime error that can suddenly appear while you are using the application. It usually occurs when the necessary DLL files required to start a QB sync session are not properly registered on the system.

When this error occurs, it displays an error message on your screen: “ Error: 2147221164(80040154) Class not registered has occurred in the following procedure: StartQBSession.”
Key Factors Leading to the Error 2147221164 on Your QuickBooks Desktop
To understand more clearly the QuickBooks Enterprise error code 2147221164 on your QuickBooks Desktop, let’s see its reasons behind the occurrence:
QuickBooks was installed on the system before Microsoft Office or Excel
Microsoft Excel is not functioning correctly
QuickBooks is running on an outdated version
The computer does not meet the QuickBooks application's compatibility requirements
Note:- QuickBooks Error 15222 occurs during updates when digital signature verification fails, caused by security settings, outdated software, or blocked internet connections.
Proven Methods to Eliminate the QuickBooks Error 2147221164 in 5 Minutes
Let’s proceed to the resolving segment, where you will get the best methods to fix the error code 2147221164 in your QBDT:
Method 1: Update your QBDT app
Initiate with the launch of the QB application
Then click the Help tab > choose the Update QuickBooks Desktop
Hit the Update Now, then look for the Reset Update option
Now, you need to press the Get Updates button > and eliminate the previously downloaded updates
Press OK to continue with the next process
As the download is finished, you have to return to the application > relaunch it to start the installation procedure
Method 2: Fix the office app on the device
First, begin the process by hitting the Start button, then choosing Apps and Features from the menu
Pick the Microsoft Excel option under the list and hit the Modify button
Now, you’ll see different repair options based on whether your Office installation is Click-to-Run or MSI-based
You can follow the appropriate steps depending on the type of installation you’re using
After that, go through the on-screen notifications to finish the repair procedures for the office suite
Method 3: Automate the Internet Explorer ETW collector
Click the Windows + R keys to access the Run window
Then mention in the text services.msc > click the Enter button
Now, as a new window opens, you have to find the Internet ETW Collector Services option in the list
Then press it and choose Properties
Proceed to the Start-up option > pick Automatic
After that, right-tap it > press Start
At the end, close all the windows and restart the app
Method 4: Reinstall the Office 32-bit version
First, uninstall the Office 365 version that you have recently been using
Then move to Office.com > sign in to your account
Now, click on the Install Office option link
Then pick the Other Install options under the list that displays on your screen
Now, press the View apps and devices button
Lastly, select the Office, language, and version under the result page > you need to select the 32-bit edition under the 32 or 64-bit
QuickBooks Error 2147221164 – Frequently Asked Questions
What is QuickBooks Error 2147221164
QuickBooks Error 2147221164 is a runtime or activation-related error that occurs when the software fails to communicate with essential system components.
Why does QuickBooks Error 2147221164 occur
This error can happen due to corrupted QuickBooks installation, damaged registry files, outdated Windows components, or conflicts with third-party software.
Can QuickBooks Error 2147221164 prevent opening the software
Yes, this error may block QuickBooks from launching properly, causing unexpected crashes or preventing access to company files.
Does QuickBooks Error 2147221164 affect all company files
QuickBooks Error 2147221164 generally affects the software globally, but individual company files may still open if the installation itself is functional.
Can system updates cause QuickBooks Error 2147221164
Outdated or missing Windows updates can trigger QuickBooks Error 2147221164 because critical system libraries required for QuickBooks operation are unavailable.
Is QuickBooks Error 2147221164 related to licensing issues
Yes, licensing or activation failures can trigger QuickBooks Error 2147221164, especially if product registration information is corrupt or unreadable.
How can QuickBooks Error 2147221164 be resolved
Resolving this error often involves repairing QuickBooks installation, updating Windows, running as administrator, and checking for software conflicts.
Can antivirus or firewall software trigger QuickBooks Error 2147221164
Yes, security software can block QuickBooks processes, causing Error 2147221164 if certain components are prevented from executing.
Is QuickBooks Error 2147221164 common in multi-user mode
QuickBooks Error 2147221164 can appear in both single and multi-user setups, especially when network permissions or hosting settings are misconfigured.
Does QuickBooks Error 2147221164 require professional support
If self-troubleshooting fails, contacting QuickBooks support is recommended to safely repair the installation and prevent recurring runtime errors.
Can registry issues lead to QuickBooks Error 2147221164
Corrupted or invalid Windows registry entries related to QuickBooks can trigger Error 2147221164, making registry cleanup or repair a crucial step.
Will reinstalling QuickBooks fix Error 2147221164
Completely uninstalling and reinstalling QuickBooks often resolves Error 2147221164 by eliminating corrupted files and restoring default system configurations.
You should also know:- QuickBooks Error 1723 appears when Windows installer detects corrupt or missing files, preventing QuickBooks installation or proper update execution.
Conclusion
This blog will guide you to rectify the interruption of the QuickBooks error 2147221164 from your desktop with the help of the given methods above in the segments. However, if you need any expert advice, you need to dial +1(855)-510-6487 and connect with the team smoothly. They will help you.




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